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Current Opportunities

Principal Investigator - Toronto, Ontario

Position: Principal Investigator
Site: MaRS Centre, Toronto
Department: Informatics & Bio-computing
Reports To: Director, Informatics & Bio-computing Platform
Salary: Commensurate with level of experience
Hours: 35 Hrs/week
Status: Full-time, Permanent  

The Ontario Institute for Cancer Research (OICR) is seeking Junior, Intermediate and Senior Principal Investigators (PIs) in Bioinformatics, Computational Biology and Biostatistics to undertake world-class computational research in a wide range of research areas, including any of the following: (1) discovery of key genetic alterations in the initiation or progression of cancer; (2) identification of biomarkers indicative of tumour subtypes or predictive of response to targeted therapy; (3) modeling of regulatory networks relevant to disease pathways; (4) analysis of genetic and environmental risk factors for cancer in patient populations; (5) use of machine learning and/or biostatistical approaches to develop novel algorithms and computational techniques for genomic and/or epigenomic data; (6) development of interoperability standards for exchanging and collaboratively annotating genome-scale data sets; or (7) development of software engineering techniques for managing and manipulating genome-scale datasets and complex analytic workflows. We expect to appoint up to five PIs over the period 2012-2014.

PIs will be expected to mentor trainees, and to build collaborations both within and outside the OICR community. In addition to base funds provided by the Institute to support the PI's salary and personnel, PIs are expected to raise additional research funds from external competitive granting agencies. The OICR will assist PIs in obtaining faculty appointments at the University of Toronto or another affiliated academic institution.


  • An MD or PhD with a proven track record in computational biology, bioinformatics,  or biostatistics;
  • For new PIs, a record of independent research and either first-author peer reviewed publications or the publication of software, databases or other significant community resources.
  • For senior and intermediate-level PIs, international recognition and a strong publication record of relevance, proven leadership and management experience including the building of strong research teams, as well as a strong record of mentorship and/or teaching;
  • Eligible to hold the rank of assistant, associate or full professor at an Ontario university;
  • Excellent communication and presentation skills.

OICR is an innovative cancer research institute located in the MaRS Centre in the Discovery District in downtown Toronto. OICR is addressing significant challenges in cancer research with multi-disciplinary, multi-institutional teams. New discoveries to prevent, detect and treat cancer will be moved from the bench to practical applications in patients. The OICR team is growing quickly. We are innovative, dedicated professionals who bring expertise to each of our roles. We are looking for individuals interested in being part of a culture of excellence that will result in Ontario being recognized internationally as a leading jurisdiction for cancer research.

Launched in December 2005, OICR is an independent institute funded by the Government of Ontario through the Ministry of Research and Innovation.

For more information about OICR, please visit the website at

RE- POSTED DATE:  March 9, 2015 
CLOSING DATE: Posted until filled

OICR has a diverse workforce and is an equal opportunity employer.

The Ontario Institute for Cancer Research thanks all applicants. However, only those under consideration will be contacted.  Candidates will be expected to provide their current employer as a reference.

Resume Format:  If you elect to apply, you will need a text or HTML version of your resume so that you can cut and paste it into the application box provided. Before you submit the completed application, you will be asked to attach one or two files to your application.  Please attach your resume as a .doc file.

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