Ontario Institute for Cancer Research
     Current Opportunities
     Keyword Search
     Career Alerts

Current Opportunities

Principal Investigator - Toronto, Ontario

Position: Principal Investigator
Site: MaRS Centre, Toronto
Department: Informatics
Reports To: Director, Informatics 
Salary: Commensurate with level of experience
Hours: 35 Hrs/ Week
Status: Full-Time, Permanent

The Ontario Institute for Cancer Research (OICR) is seeking a Principal Investigator (PI) in Informatics to undertake world-class computational research. We seek to strengthen and complement our existing expertise in cancer genomics, machine-learning, analysis of next-generation sequencing, knowledge-bases and pathway/network analysis. We welcome applications from computational biologists of all types, but a career focus on cancer research is critical going forward.

The PI will be expected to mentor trainees, and to build collaborations both within and outside the OICR community. In addition to base funds provided by the Institute to support the PI's salary and personnel, the PI is expected to raise additional research funds from external competitive granting agencies. The OICR will assist the PI in obtaining faculty appointments at the University of Toronto or another affiliated academic institution.

OICR’s IBC Program is the home of the ICGC Data Coordination Centre, leads analysis for two ICGC projects (PanCuRx and CPC-GENE), the Ontario Health Study and numerous other large-scale studies. It is the home of multiple international projects (e.g. Reactome, ICGC-TCGA DREAM Somatic Mutation Calling Challenge) and provides a robust intellectual environment for computational biology. A ~10,000-CPU institutional cluster is available to support analysis by the Program.


  • An MD or PhD with a proven track record in computational biology, bioinformatics, or biostatistics
  • For new PIs, a record of independent research and either first-author peer reviewed publications or the publication of software, databases or other significant community resources.
  • For senior and intermediate-level PIs, international recognition and a strong publication record of relevance, proven leadership and management experience including the building of strong research teams, as well as a strong record of grant-funding and mentorship.
  • Excellent communication and presentation skills.
  • Strong writing skills.

Please attach the following to your application:

  • A covering letter, including the names of 3 potential referees
  • A complete academic CV in PDF format
  • A 2-4 page proposed research document, including a section highlighting relevance of the proposed studies to cancer

OICR is an innovative cancer research institute located in the MaRS Centre in the Discovery District in downtown Toronto. OICR is addressing significant challenges in cancer research with multi-disciplinary, multi-institutional teams. New discoveries to prevent, detect and treat cancer will be moved from the bench to practical applications in patients. The OICR team is growing quickly. We are innovative, dedicated professionals who bring expertise to each of our roles. We are looking for individuals interested in being part of a culture of excellence that will result in Ontario being recognized internationally as a leading jurisdiction for cancer research.

Launched in December 2005, OICR is an independent institute funded by the Government of Ontario through the Ministry of Research and Innovation.

For more information about OICR, please visit the website at www.oicr.on.ca.

This job posting is part of an ongoing recruitment initiative, resumes will be reviewed on a continuous basis.

OICR is an inclusive employer dedicated to building a diverse workforce. We encourage applications from all qualified candidates and will accommodate applicants’ needs throughout all stages of the recruitment and selection process. Please advise the Recruiter to ensure your accessibility needs are accommodated throughout this process. Information received relating to accommodation will be addressed confidentially.

The Ontario Institute for Cancer Research thanks all applicants. However, only those under consideration will be contacted. Candidates will be expected to provide their current employer as a reference.

Resume Format: If you elect to apply, you will need a text or HTML version of your resume so that you can cut and paste it into the application box provided. Before you submit the completed application, you will be asked to attach one or two files to your application. Please attach your resume as a .doc file.