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Current Opportunities

Junior Bioinformatician, Next-Generation Sequencing - Toronto, Ontario

Position: Junior Bioinformatician (Biological Technician), Bioinformatics
Next-Generation Sequencing
Site: MaRS Centre
Address: 661 University Avenue, suite 510. Toronto, Ontario. M5G 0A3
Department: Informatics 
Reports To: Dr. Paul C. Boutros
Salary: $50,864-$61,037
Hours: 35 Hrs/week
Status: Permanent, full-time

Are you an expert in providing technical support and assistance in biological tests and analyses with respect to next-generation sequencing data? The Boutros Lab is seeking a talented Junior Bioinformatician (Biological Technician) to assist in analyzing some of the laboratory’s largest clinical Next Generation Sequencing (NGS) datasets in the world. We want somebody with a deep interest in understanding big-data problems and an in-depth knowledge of NGS data and who is able to perform a range of technical functions in biological research. While experience with cancer NGS is preferred, a strong skillset and a corresponding ability to assist in the preparation of related reports and analysis of research data is most important as is model-organism work. This is a role for people with strong applied skills, and the ideal candidate will be able to move from IGV read-level views through to providing technical assistance in developing machine-learning models. In essence, the ideal candidate is someone who is able to assist in performing experimental procedures, setting up and conducting biological tests and laboratory analyses in support of research as well as in analyzing data and preparing reports

The datasets you would be studying can include (amongst others):

  • The Canadian Prostate Cancer Genome Network (CPC-GENE), the largest prostate cancer genomics study in the world, sequencing the whole genomes, methylomes and transcriptomes of 500 prostate cancers
  • The ICGC pan-cancer initiative, performing a meta-analysis of >2500 tumour WGS

The ICGC-TCGA DREAM Somatic Mutation Calling Challenge, a global crowd-sourcing challenge aimed at standardizing NGS analysis methods for cancer data
Your colleagues will be experts in providing technical support in the area of NGS data-analysis and machine-learning, with a track-record of publications in the highest impact journals. It is an inter-disciplinary and integrated team of bioinformaticians, biological technicians, software-engineers and statisticians. There are people here at all levels of training from full-time staff (at the Bachelors, Master’s and PhD levels) to trainees (from undergraduate to post-doctoral). Software development is professional, with test-driven development and continuous integration, and we have a ~10,000 CPU computing cluster to support our research.

This is a unique opportunity to develop your strong computational skillset and to make a major impact on our understanding of cancer. Join us in studying unique datasets that will help rewrite the textbook of cancer genomics.


  • At minimum, a college diploma in computational biology, engineering, mathematics, computer sciences or molecular biology; B.Sc. preferred.
  • At minimum, 1 year of experience with extensive exposure to cancer NGS data required
  • Strong background with Unix/Linux tools and administration
  • Solid programming skills, preferably in R/Perl, required


  • Background in machine-learning is a strong asset, but we will train for strong candidates
  • Background in biostatistics, particularly survival or Bayesian techniques
  • Experience working with test-driven programming and version control
  • Strong communication skills
  • Data-Visualization capabilities

OICR is an innovative cancer research institute located in the MaRS Centre in the Discovery District in downtown Toronto. OICR is addressing significant challenges in cancer research with multi-disciplinary, multi-institutional teams. New discoveries to prevent, detect and treat cancer will be moved from the bench to practical applications in patients. The OICR team is growing quickly. We are innovative, dedicated professionals who bring expertise to each of our roles. We are looking for individuals interested in being part of a culture of excellence that will result in Ontario being recognized internationally as a leading jurisdiction for cancer research.

Launched in December 2005, OICR is an independent institute funded by the Government of Ontario through the Ministry of Research, Innovation and Science.

For more information about OICR, please visit the website at www.oicr.on.ca.

CLOSING DATE: Until filled


All interested candidates are asked to please submit their Cover Letter & Resume online at www.oicr.on.ca/careers.

OICR is an inclusive employer dedicated to building a diverse workforce. We encourage applications from all qualified candidates and will accommodate applicants’ needs throughout all stages of the recruitment and selection process. Please advise the Recruiter to ensure your accessibility needs are accommodated throughout this process. Information received relating to accommodation will be addressed confidentially.

The Ontario Institute for Cancer Research thanks all applicants. However, only those under consideration will be contacted. Candidates will be expected to provide their current employer as a reference.

Resume Format: If you elect to apply, you will need a text or HTML version of your resume so that you can cut and paste it into the application box provided. Before you submit the completed application, you will be asked to attach one or two files to your application. Please attach your resume as a .doc file.


Group Benefits Coverage

Sick Days Ten (10) paid days per year

SunLife Group Benefits

Effective Date of Coverage:
The waiting period for your group benefits plan is three (3) months continuous employment.
Premiums are 100% paid by the Institute

Long Term Disability
Premiums are 100% paid by the Institute
Graded Schedule. Maximum is $7,500

Life Coverage
Premiums are 100% paid by the Institute
Two (2) times Annual Basic Earnings up to a maximum of $500,000

Dependent Life
Premiums are 100% paid by the Institute
$5,000 for your spouse
$2,500 per dependent child

Optional Life, Spousal Optional Life, Child Optional Life Insurance
Premiums are 100% paid by the employee
Please refer to your benefit booklet for details on this optional benefit.

Accidental Death & Dismemberment
Premiums are 100% paid by the Institute
Two (2) times Annual Basic Earnings up to a maximum of $500,000

Extended Health Care Coverage
Deductible None

Monthly Premium Monthly premiums are 100% paid by the Institute

Dependent Coverage Covered until age 21 or 25 for full-time students

Prescription Drugs 80% reimbursement
Mandatory Generic Substitution
Prior Authorization (PA) program applies to a limited number of drugs
Fertility Drugs: $2,400 per lifetime maximum
Dispensing Fee Nil

Vision Care 100% reimbursement
$300 every 12 month period for a person less than age 18;
24 month period for any other person. Includes eyeglasses, contact lenses or laser eye corrective surgery
Eye exam - $50 over 2 benefit years

Health Care Practitioners 80% reimbursement
$500 per practitioner per benefit year

Private Nursing 80% reimbursement
$25,000 during any 3 consecutive benefit years

Hearing Care 80% reimbursement
$500 in any 5 benefit year periods

Orthopedic Shoes 80% reimbursement



Extended Health Care Coverage Coverage
Orthotics 80% reimbursement
$350 per benefit year

Out-of-Province Coverage
(Emergency Services) 100% reimbursement
$1,000,000 lifetime maximum
Limited to 60 days trip duration
Hospital within Home Province 100% reimbursement
Semi private room accommodation

Dental Care Coverage
Deductible None

Monthly Premium Monthly premiums are 100% paid by the Institute

Recall Every 5 months

Basic & Minor Restorative 80% reimbursement
Diagnostic / Preventative, Restorative,
Periodontic and Endodontic Services

*Maximum Coverage
Basic & Minor Restorative
*Combined maximum of $3,000 per year for all Basic, Minor & Major Restorative

Major Restorative
Crowns, bridges and dentures
50% reimbursement
*Maximum Coverage
Crowns, bridges and dentures *Combined maximum of $3,000 per year for all Basic, Minor & Major Restorative
TMJ Treatment
(Temporomandibular Joint)
50% reimbursement
$1,000 lifetime maximum

For adults and children No coverage
Dental Fee Guide
Current Fee Guide for general practitioners


Pension Plan Coverage
Healthcare of Ontario Pension Plan
Effective date of coverage: immediate

Employee contributes 6.9% of earnings up to the year’s maximum pensionable earnings (YMPE); and 9.2% of earnings above the YMPE

The YMPE for 2016 is $54,900


Vacation Coverage

Vacation Entitlement
3 weeks (15 days) of paid vacation per year