Site: MaRS Centre, Toronto
Department: Diagnostic Development
Reports To: Director, Diagnostic Development
Salary: Commensurate with level of experience
Hours: 35 hours/week
Status: Full-time, Temporary (Two years, with potential for renewal)
The Ontario Institute for Cancer Research (OICR) is seeking a talented Biostatistician to join the Diagnostic Development (DD) program, which is focused on the development and validation of clinical assays to improve therapeutic selection for early cancers. The program aims to develop personalized medicine approaches that maximize the chance of positive outcomes for those diagnosed with cancer. The DD program includes internationally-recognized experts in biomarker discovery and validation, and actively works with diagnostics industry and biotech companies. Current work includes the use of next generation sequencing and gene expression analysis to discover biomarkers that stratify risk in breast cancer and prostate cancer, and the development of the methods needed to translate those biomarkers into the clinical laboratory. This position is closely integrated into both existing research programs and the development of innovative clinical trials in partnership with the Ottawa Hospital and the REthinking Clinical Trials (REaCT) Program.
The Biostatistician will join the DD Program, analyzing clinical cohorts with integrated biomarker analysis. A large portion of their time will also be focused on supporting the development, design and analysis of novel early clinical trials, both internally and for our external partners and collaborators.
This position will be based out of Toronto, however, travel to Ottawa will be required.
To find out more about what’s happening in Diagnostic Development, visit OICR News.
- Serve as biostatistics representative on early phase clinical trial development teams, partner with cross-functional members and provide statistical and strategic input on clinical development plans;
- Provide expertise on the development of clinical trials, including the framing of research questions, determining outcomes and how they are measured, sample size calculations, as well as providing input in grant applications, including and reviewing and writing sections of the grant proposal;
- Determine appropriate methods of statistical analyses based on in-depth knowledge, discussions with collaborators, and by reviewing the current literature;
- Update, optimize and maintain in-house datasets, and generate reports;
- As needed, serve as an biostatistical reviewer for internal clinical trial review and decision making;
- As needed, provide statistical support for external stakeholders; and
- Other assigned analysis tasks.
- Master's degree in biostatistics or statistics with significant bioinformatics experience, or Undergraduate degree and equivalent experience;
- Preference provided to applicants with experience in oncology clinical research;
- Technical skills in statistical and software packages - SAS, Stata, R, Word, PowerPoint, etc.;
- Expertise in statistical techniques – logistic and Cox regression, generalized linear models, large database analyses, dimension reduction, among others;
- Be highly self-motivated and detail-oriented; and
- Strong verbal and written communication skills.
OICR is an innovative cancer research institute located in the MaRS Centre in the Discovery District in downtown Toronto. OICR is addressing significant challenges in cancer research with multi-disciplinary, multi-institutional teams. New discoveries to prevent, detect and treat cancer will be moved from the bench to practical applications in patients. The OICR team is growing quickly. We are innovative, dedicated professionals who bring expertise to each of our roles. We are looking for individuals interested in being part of a culture of excellence that will result in Ontario being recognized internationally as a leading jurisdiction for cancer research.
Launched in December 2005, OICR is an independent institute funded by the Government of Ontario through the Ministry of Colleges and Universities.
For more information about OICR, please visit the website at www.oicr.on.ca.
CLOSING DATE: Until Filled
OICR is an inclusive employer dedicated to building a diverse workforce. We encourage applications from all qualified candidates and will accommodate applicants’ needs throughout all stages of the recruitment and selection process. Please advise the Recruiter to ensure your accessibility needs are accommodated throughout this process. Information received relating to accommodation will be addressed confidentially.
The Ontario Institute for Cancer Research thanks all applicants. However, only those under consideration will be contacted.
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