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Current Opportunities

Postdoctoral Fellow, Medicinal Chemistry - Toronto, Ontario

Position: Postdoctoral Fellow, Medicinal Chemistry
Site: MaRS Centre, Toronto
Department: Drug Discovery Program
Reports To: Head, Therapeutic Innovation and Drug Discovery
Salary: Commensurate with level of experience
Hours: 35 hours/week
Status: Full-time, Temporary (2 year contract)

The Ontario Institute for Cancer Research (OICR) is seeking a post-doctoral fellow with organic/medicinal chemistry experience to join the Drug Discovery Program for a 2 year contract.

Learn more about working at OICR here.

The OICR Drug Discovery Program is one of the largest programs of its kind in Canada. Our mission is to help efficiently translate discoveries made in Ontario’s labs into novel oncology therapies. The team is comprised of more than 25 researchers whose collective expertise spans the entire drug discovery process from target identification and validation to clinical candidate selection. The group has extensive drug discovery experience within pharma and biotech environments and combines the disciplines of biology, ADME/PK, analytical, medicinal and computational chemistry expertise along with state-of-the-art infrastructure necessary to successfully conduct drug discovery projects.

To find out more about what’s happening in Drug Discovery, visit OICR News


  • Design and synthesize small molecule drug candidates against anti-cancer targets;
  • Maintain records of experimental procedures and data;
  • Liaise effectively with multi-disciplinary team members (computational chemistry, biology, and ADME groups) and academic collaborators;
  • Participate in team meetings, both internal and external;
  • Present results to internal and external audiences, including at international meetings, and contribute to manuscripts for peer-reviewed journals;
  • Assist in day-to-day lab management; 
  • Work effectively under pressure and tight timelines; and
  • Adhere to all OICR safety guidelines and policies, strongly advocate safety to others


  • PhD in Synthetic Organic, Medicinal Chemistry or related field;
  • Recent graduate; relevant experience in an industrial/academic drug discovery environment would be an asset;
  • Proven track record in organic/medicinal chemistry, demonstrated by a good publication record;
  • Comprehensive knowledge of organic chemistry;
  • Strong knowledge and experience in compound purification and characterization (automated chromatography, HPLC, NMR, MS);
  • Demonstrated ability to work independently and as part of a team;
  • Attention to detail and strong organizational skills; and
  • Excellent verbal and written communication skills.

OICR is a collaborative, not-for-profit research institute accelerating the development of new cancer research discoveries for patients around the world while maximizing the economic benefit of this research for the people of Ontario. We are dedicated professionals who bring expertise to each of our roles. We are looking for individuals who share our values of excellence, innovation, collaboration, impact, responsibility and community.

Launched in December 2005, OICR is an independent institute funded by the Government of Ontario through the Ministry of Colleges and Universities.

For more information about OICR, please visit the website at www.oicr.on.ca.

CLOSING DATE: Until Filled

OICR is an inclusive employer dedicated to building a diverse workforce. We encourage applications from all qualified candidates and will accommodate applicants’ needs throughout all stages of the recruitment and selection process. Please advise the Recruiter to ensure your accessibility needs are accommodated throughout this process. Information received relating to accommodation will be addressed confidentially.

The Ontario Institute for Cancer Research thanks all applicants. However, only those under consideration will be contacted.

Resume Format: If you elect to apply, you will need a text or HTML version of your resume so that you can cut and paste it into the application box provided. Before you submit the completed application, you will be asked to attach one or two files to your application. Please attach your resume as a .pdf or .doc file.