Careers at UHN

Job Description

Postdoctoral Fellow - Toronto, Ontario

Job Posting #836608

Position: Postdoctoral Fellow
Site: Toronto Western Hospital – Krembil Discovery Tower
Department: Neuroscience
Reports to: Principal Investigator
Hours: 35 hours per week
Status: Temporary Full-time (up to 3 years)

University Health Network (UHN) is looking for an experienced professional to fill the key role of Postdoctoral Fellow in our Neuroscience Department.

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The University Health Network, where “above all else the needs of patients come first”, encompasses Toronto Rehabilitation Institute, Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre and the Michener Institute of Education at UHN. The breadth of research, the complexity of the cases treated, and the magnitude of its educational enterprise has made UHN a national and international resource for patient care, research and education. With a long tradition of groundbreaking firsts and a purpose of “Transforming lives and communities through excellence in care, discovery and learning”, the University Health Network (UHN), Canada’s largest research teaching hospital, brings together over 16,000 employees, more than 1,200 physicians, 8,000+ students, and many volunteers. UHN is a caring, creative place where amazing people are amazing the world.

University Health Network (UHN) is a research hospital affiliated with the University of Toronto and a member of the Toronto Academic Health Science Network. The scope of research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. Research across UHN's five research institutes spans the full spectrum of diseases and disciplines, including cancer, cardiovascular sciences, transplantation, neural and sensory sciences, musculoskeletal health, rehabilitation sciences, and community and population health. Find out about our purpose, values and principles here.

We are seeking a highly motivated Postdoctoral Fellow with a background in experimental neuroscience and patch-clamp electrophysiology and an interest in data science and genomics. The fellow will lead an innovative project studying the physiology of human cortical neurons resected during neurosurgery. The fellow will have the opportunity to shape the details of the project based on their specific interests.Potential project ideas include: 1) comparing the how aspects of neuron physiology differ between humans and mice; 2) correlating subject-specific demographic and genetic differences with intrinsic or synaptic physiology; 3) studying how human-specific circuit motifs may support oscillatory synchrony. Since human neurological tissue is only available at specific times, the fellow will also have opportunities to contribute to other collaborative projects in the Valiante and Tripathy Labs.

This project is a collaboration between the Neuron to Brain Lab at the Krembil Research Institute ( and the Lab of Computational Genomics at the Centre for Addiction and Mental Health ( Both laboratories are located a short distance from each other in downtown Toronto.

The ideal candidate for this position will have:
• A PhD degree within the past 5 years in neuroscience or equivalent area
• Considerable expertise performing patch-clamp electrophysiology on ex vivo brain slices
• A track record for independent research and a strong publication record
• Experience writing custom data analysis scripts in a programming language or a strong desire to learn
• Familiarity with molecular biology techniques and gene expression analysis
• Experience with cell or slice culture

The successful candidate will also be expected to apply for independent research fellowships.

A complete application should include a brief cover letter, curriculum vitae, and the 2-3 letters of references. Please submit your online application with the title ‘Postdoctoral fellowship in patch-clamp electrophysiology’ in the subject line of your cover letter. You will also be required to complete some initial screening questions.

Posted Date: January 24, 2019                 Closing Date: Until filled

UHN thanks all applicants, however, only those selected for an interview will be contacted.

UHN is a respectful, caring, and inclusive workplace. We are committed to championing accessibility, diversity and equal opportunity. Requests for accommodation can be made at any stage of the recruitment process providing the applicant has met the Bona-fide requirements for the open position. Applicants need to make their requirements known when contacted.

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